Deutsch Intern
    Sonderforschungsbereich 688
    Cellular Neuroimaging: T2-w MRI of a small cortical infarct at day 6, 24 hrs after systemic application of an iron-contrast agent (SPIO). The hypointense (black) rim represents the invasion of iron-laden macrophages from the circulation into the infarct within the last 24 hrs.

    Cell-Cell interactions in cerebral infarct pathogenesis: Molecular MR-Imaging and thrombocyte function

    G. StollB. Nieswandt


    The interdisciplinary project B01 (Stoll/Nieswandt) takes advantage of novel MR contrast agents to visualize in-vivo the cellular and molecular processes involved in the development of cerebral infarcts. In a therapeutic approach we furthermore use pharmacological and transgenic mouse models to evaluate the role of platetets and coagulation factors during secondary infarct growth after middle cerebral artery occlusion.


    SFB 688 Mechanisms and imaging of cardiovascular cell-cell-interactions
    Josef-Schneider-Straße 2
    97080 Würzburg


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